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Dr. Alfredo Bruno (CEO)

After finishing his M. Sc. in Computational Quantum Chemistry and a Ph.D. in Laser Physics in the University of Saskatchewan, Canada, Alfredo came to work in the TU and Max-Plank Institute in Munich as an Alexander-von-Humboldt (AvH) fellow followed by an academic position in the University of Zürich.

He joined Novartis (former Ciba-Geigy) in 1988 where he headed several R&D projects in collaboration with Spectra-Physics and Chiron Diagnostics (US). In 2004 he founded TLT Medical Ltd as a spin-off from Novartis with a therapy for Onychomycosis he invented where he was the CEO until it was sold to Arpida Ltd in 2007. In Arpida he was the Head of Antifungals until 2008 when the company exited in a merge. Subsequently he then co-founded FreiBiotics as a spin-off from the University of Freiburg (Germany) in 2008, a company dedicated to the discovery of new antibiotics, where he was the CEO until the end of 2011.

Dr. Bruno has more than 50 peer reviewed scientific publications and more than 15 patents and was the Associated Editor of various peer-reviewed journals.

Prof. Dr. Philippe Cattin (CTO & Head of Development):

He earned his Ph.D. at the Institute of Robotics (ETH Zürich, Switzerland). Later on he joined the computer vision laboratory at ETH Zurich where he was heading the medical image analysis group before being appointed as Professor to the University of Basel, Switzerland. Prof. Cattin has good contacts to the robotics and computer vision community in Switzerland and other countries. He founded and became the head of the Medical Image Analysis Center ( of the University of Basel and University Hospital Basel. As he continues his academic functions and works in AOT he directs the Ph.D. thesis of various students in AOT related projects.

PD Dr. Dr. Philipp Jürgens (Head of Clinical R&D)

Dr. Jürgens is working as a chief clinician in the Dept. of Oral & Maxillofacial Surgery at University Hospital Basel. After finishing medical and dental school in Munich he passed his residency in CMF surgery at Technische Universität München and University Hospital Basel. His main clinical focus is the surgical correction of malocclusions (orthognatic surgery) and reconstructive facial surgery. Scientifically he covers a broad spectrum form tissue engineering, medical rapid prototyping and rapid manufacturing to virtual treatment planning and simulation, intraoperative navigation and robot-guided surgery. From 2002 until 2005 he was the coordinating manager of the Bavarian Research Network for Tissue Engineering and Rapid Prototyping and, from 2005-2009 Dr. Jürgens was deputy project leader of the CMF Project within the NCCR-CoMe (National Center of Competence in Research for Computer Aided and Image Guided Medical Interventions) sponsored by the Swiss National Science Foundation. During the last phase of CoMe, from 2009 until 2013 he shared the project lead with Prof. Cattin. Currently he is heading the research unit Computer-Assisted Cranio-Maxillo-Facial Surgery (CACMFS).

Prof. Dr. Hans-Florian Zeilhofer

Prof. Zeilhofer is head of the Dept. of Oral & Maxillofacial surgery at the University Hospital Basel and at Kantonsspital Aarau and Head of the adjacent Hightech- Research Center. Prof. Zeilhofer is the spokesman of the research focus “clinical morphology and biomedical engineering” at the Faculty of Medicine at Basel University and he is currently the President of the Swiss Society of Oral and Maxillofacial Surgeons. As an internationally recognized KOL in CMF surgery ( with a special focus on new and innovative technologies he is scientific advisor for a number of institutions and research projects.